Research Profiles: Improved CE/MALDI-TOF MS interface.

MALDI-TOF MS in Prenatal Genomics.

Prenatal diagnosis aims either to provide the reassurance to the couples at risk of having an affected child by timely appropriate therapy or to give the parents a chance to decide the fate of the unborn babies with health problems. Invasive prenatal diagnosis (IPD) is accurate, however, carrying a risk of miscarriage. Non-invasive prenatal diagnosis (NIPD) has been developed based on the exist...

PrepMS: TOF MS data graphical preprocessing tool

UNLABELLED We introduce a simple-to-use graphical tool that enables researchers to easily prepare time-of-flight mass spectrometry data for analysis. For ease of use, the graphical executable provides default parameter settings, experimentally determined to work well in most situations. These values, if desired, can be changed by the user. PrepMS is a stand-alone application made freely availab...

Characterization of fengycin homologues produced by Bacillus subtilis K1 by MALDI-TOF tandem mass spectrometry (MALDI TOF MS/MS)

Phytochemical analysis of Cyperus rotundus hexane fraction by GC-MS and total oligomeric flavonoid fraction by 4D GCXGC TOF-MS

Cyperus rotundus (CR) is a traditional medicinal herb, and recent studies demonstrated its pharmacological effects to cure neurological disorders. In our earlier reports, we also found that CR exerts anxiolytic effects and improves memory impairment in hypoxia-induced rats. In vitro CR also effectively ameliorates oxidative stress-induced SH-SY5Y neuronal cell damage. In the present study, we e...

Comparative proteomics analysis of human osteosarcoma by 2D DIGE with MALDI-TOF/TOF MS

Osteosarcoma (OS) is the most common primary malignant tumor of bone and the third most common cancer in childhood and adolescence. However, controversy concerning the ideal combination of chemotherapy agents ensued throughout the last quarter of the 20th century because of conflicting and often nonrandomized data. Collaborative efforts to increase understanding of the biology of osteosarcoma a...